What it is & general benefits

Lactobacillus acidophilus is a lactic acid–producing probiotic naturally found in the
gut and female urogenital tract. By making lactic acid and other organic acids, it helps keep
local pH slightly acidic and makes it harder for unwanted bacteria to overgrow. Human studies
with probiotic Lactobacillus show benefits for digestive comfort and support of a balanced
vaginal microbiota and normal immune function in women.1,2

Why we use it in Women's Probiotics

In Women’s Probiotics, L. acidophilus is one of the core strains that helps maintain a
Lactobacillus-dominant environment in both the gut and vaginal tract. Its role is to support
healthy vaginal pH and everyday microbial balance, providing front-line competition against
disruptive bacteria while also contributing to overall comfort and immune resilience.

References

1. Wu LY et al. Probiotics and women’s health. Taiwan J Obstet Gynecol. 2024.

2. Falagas ME et al. Probiotics for bacterial vaginosis. Clin Microbiol Infect. 2007.

What it is & general benefits

Lactobacillus plantarum is a lactic acid–producing probiotic commonly found in
fermented foods and in the human gut. It can help modulate the intestinal microbiota,
reinforce gut-barrier integrity and influence immune signaling, which in clinical studies has
been linked to improvements in digestive comfort and reduced frequency or intensity of some
gastrointestinal symptoms when used as a probiotic strain.1,2

Why we use it in Women's Probiotics

In Women’s Probiotics, L. plantarum is included as a versatile strain that supports
both gut and vaginal balance. Certain L. plantarum strains show the ability to adhere
to vaginal epithelial cells and reduce the adhesion of unwanted microbes, helping maintain a
Lactobacillus-dominant environment and comfortable vaginal pH.3 At the same time,
its effects on gut microbiota and mucosal immunity make it a useful partner strain for daily
digestive comfort and overall resilience in women.

References

1. Zare D et al. Health benefits of Lactiplantibacillus plantarum. Probiotics Antimicrob Proteins. 2024.

2. Aljohani A et al. Clinical applications of L. plantarum probiotics. Probiotics Antimicrob Proteins. 2024.

3. De Seta F et al. L. plantarum P17630 and vaginal Candida control. J Funct Foods. 2014.

What it is & general benefits

Lactobacillus casei is a lactic acid–producing probiotic widely used in fermented
dairy drinks and studied as a supplement strain. It can help modulate the gut microbiota,
support intestinal barrier function and influence mucosal immune responses. Clinical trials
with specific L. casei strains (such as Shirota) report improvements in certain
gastrointestinal symptoms, including constipation and antibiotic-associated diarrhea, and a
reduction in common infection episodes in some groups of participants.1–3

Why we use it in Women's Probiotics

In Women’s Probiotics, L. casei is added as a “gut–immune support” strain that
complements the more vaginal-focused Lactobacillus species. Its role is to reinforce daily
digestive comfort and help maintain a balanced gut ecosystem, which in turn feeds into the
gut–vaginal axis and overall immune resilience. By pairing L. casei with
Lactobacillus strains that more directly colonize the vaginal tract, the formula aims to
support women from the inside out, starting in the intestine where many Lactobacilli are
originally hosted.

References

1. Koebnick C et al. Probiotic beverage containing L. casei Shirota improves
gastrointestinal symptoms in chronic constipation. Can J Gastroenterol. 2003.

2. Wong S et al. L. casei Shirota reduces antibiotic-associated diarrhoea.
Br J Nutr. 2014.

3. Galdeano CM, Perdigón G. L. casei activates gut mucosal immune responses.
Clin Vaccine Immunol. 2006.

What it is & general benefits

Lactobacillus paracasei is a lactic acid–producing probiotic closely related to
L. casei and naturally found in fermented foods and the human gut. Specific
L. paracasei strains can adhere to intestinal cells, help stabilise the gut barrier
and modulate immune responses. Clinical studies report benefits for digestive comfort and a
reduced risk or duration of common infections when certain strains are used regularly as
probiotics.1,2

Why we use it in Women's Probiotics

In Women’s Probiotics, L. paracasei is included as a “bridge” strain between gut and
immune support. Its role is to back up everyday intestinal balance and help fine-tune mucosal
immunity, which indirectly supports the gut–vaginal axis and resilience against disruptive
microbes. Combined with more strongly vaginal-colonising Lactobacillus species, it helps build
a broader, multi-strain foundation for women’s daily comfort and immune defence.

References

1. Tsai YT et al. Adhesion and immunomodulatory properties of L. paracasei. Appl Environ Microbiol. 2010.

2. Maidens C et al. Probiotic L. paracasei and resistance to common infections.
Eur J Nutr. 2013.

What it is & general benefits

Often classified as Lactobacillus delbrueckii subsp. bulgaricus, this lactic
acid–producing bacterium is a traditional yogurt starter and a well-studied probiotic
candidate. It helps ferment lactose into lactic acid, creating an acidic environment that
supports beneficial microbes and makes it harder for unwanted bacteria to thrive. Recent
preclinical and clinical work suggests selected L. bulgaricus strains can promote a
more balanced intestinal flora, support gut-barrier integrity, modulate inflammation and
contribute to healthier lipid and metabolic markers in people with overweight when consumed
regularly as a probiotic.1–3

Why we use it in Women's Probiotics

In Women’s Probiotics, L. bulgaricus is used as a “fermenting workhorse” strain that
primarily supports the gut side of women’s health. Its role is to help maintain an acidic,
Lactobacillus-friendly intestinal environment and to back up everyday digestive comfort and
immune balance. By pairing this traditional yogurt strain with more vaginal-focused
Lactobacillus species, the formula aims to offer broader, daily support for women whose
lifestyles or diets may challenge both gut and systemic resilience.

References

1. de Jesus LCL et al. Health-promoting effects and safety aspects of
L. delbrueckii subsp. bulgaricus. J Funct Foods. 2024.

2. Chu PY et al. L. bulgaricus supplementation and body weight/lipids in overweight
adults. Metabolites. 2024.

3. Evivie SE et al. Probiotic properties of L. bulgaricus KLDS 1.0207.
Front Microbiol. 2020.

What it is & general benefits

Lactobacillus brevis is a lactic acid–producing probiotic found in fermented foods
such as sauerkraut and pickles as well as in the human gut. Selected L. brevis
strains can help stabilise the intestinal microbiota, support antioxidant defences and modulate
immune responses. Human and animal studies report that specific strains improve redox balance,
ease some stress-related or inflammatory changes and may lower the risk or duration of common
infections when used regularly as a probiotic.1–3

Why we use it in Women's Probiotics

In Women’s Probiotics, L. brevis is used as a gut–immune and “comfort” strain that
complements more vaginal-focused Lactobacillus species. Its role is to help maintain a
Lactobacillus-friendly intestinal environment, support everyday immune tone and provide
antioxidant backing along the gut–skin and gut–brain axes. This makes it a useful partner for
women whose busy lifestyles can challenge digestion, stress resilience and overall comfort.

References

1. Olekhnovich EI et al. Physiological effects of L. brevis 47f under stress.
Microb Cell Fact. 2021.

2. Waki N et al. Effects of dietary L. brevis KB290 on influenza incidence.
Lett Appl Microbiol. 2014.

3. Cho YH et al. L. brevis-derived exosomes and skin barrier support.
Clin Cosmet Investig Dermatol. 2025.

What it is & general benefits

Lactobacillus reuteri (now often named Limosilactobacillus reuteri) is a
lactic acid–producing probiotic that naturally inhabits the human gut and urogenital tract.
It can make antimicrobial compounds such as reuterin, compete with unwanted microbes and
interact with the intestinal immune system. Clinical and mechanistic studies show that
selected L. reuteri strains help support digestive comfort, modulate inflammatory
markers and are generally safe and well tolerated when used as probiotics in adults.1–3

Why we use it in Women's Probiotics

In Women’s Probiotics, L. reuteri is included as a key strain for the gut–vaginal
axis. In combination with other Lactobacillus species, it helps maintain a Lactobacillus-rich,
low-pH environment that makes it harder for disruptive bacteria and yeasts to dominate, while
also supporting balanced immune signalling in the gut mucosa. This dual action—local
microbial competition plus immune modulation—makes L. reuteri a useful partner for
everyday vaginal comfort, recurrent balance support and overall resilience in women.

References

1. Peng Y et al. Lactobacillus reuteri in digestive system diseases.
World J Gastroenterol. 2023.

2. Tenorio-Jiménez C et al. L. reuteri V3401 reduces inflammatory biomarkers in
metabolic syndrome. Nutrients. 2019.

3. Mangalat N et al. Safety and tolerability of L. reuteri DSM 17938 in adults.
PLoS One. 2012.

What it is & general benefits

Also known as Ligilactobacillus salivarius, this lactic acid–producing probiotic is
naturally found in the mouth, gut and female genital tract. Many strains show strong adhesion
to mucosal surfaces and produce organic acids and antimicrobial substances that help suppress
unwanted microbes. Recent reviews highlight its ability to support gut microbial balance,
antioxidant defences and healthy immune signalling when used as a probiotic in humans.1,2

Why we use it in Women's Probiotics

In Women’s Probiotics, L. salivarius is positioned as a specialist for the
gut–vaginal axis. Specific strains have been studied for their capacity to adhere to vaginal
epithelium, lower pH through lactic acid production and inhibit common vaginal opportunists,
while remaining compatible with other Lactobacillus species in the microbiota.3,4
Combined with the rest of the blend, its role is to help maintain a Lactobacillus-dominant
vaginal ecosystem, comfortable pH and everyday reproductive well-being from the inside out.

References

1. Yang Y et al. Understanding Ligilactobacillus salivarius from probiotic to
microbiome therapeutics. Compr Rev Food Sci Food Saf. 2024.

2. Gul S et al. Health benefits of probiotics: a clinical reappraisal.
J Clin Med. 2024.

3. Fernández L et al. L. salivarius CECT5713 and female reproductive microbiota.
Nutrients. 2021. 4. Kim SY et al. L. salivarius CLS0420 and vaginal
well-being in healthy women. Probiotics Antimicrob Proteins. 2025.

What it is & general benefits

Lactobacillus fermentum is a lactic acid–producing probiotic species now often
classified as Limosilactobacillus fermentum. It naturally occurs in the human gut,
mouth and female genital tract. Selected strains can adhere to mucosal surfaces, produce
organic acids and antimicrobial substances, and modulate immune signalling. Recent reviews
describe L. fermentum as a candidate for strengthening immune defences and helping
to reduce the risk of some gastrointestinal and respiratory infections when used as part of a
probiotic regimen.1,2

Why we use it in Women's Probiotics

In Women’s Probiotics, L. fermentum is included as a specialist for vaginal
balance and antifungal defence along the gut–vaginal axis. Clinical and preclinical studies
with specific L. fermentum strains show the ability to lower vaginal overgrowth of
organisms such as Candida, support a Lactobacillus-dominant, low-pH environment and
favourably influence the gut microbiota at the same time.2,3 In this formula, its
role is to work alongside other Lactobacillus species to help maintain everyday vaginal
comfort, support recurrent balance and back up immune resilience from the inside out.

References

1. Kaur K et al. Probiotic applications in infectious diseases. Diseases. 2025.

2. Pane M et al. L. fermentum for vulvovaginal health: randomized clinical trial.
Front Microbiol. 2024.

3. Jang SJ et al. L. fermentum KBL674 and vaginal Candida burden in mice.
Probiotics Antimicrob Proteins. 2024.

What it is & general benefits

Lactobacillus gasseri is a lactic acid–producing probiotic naturally found in the
human gut and vaginal tract. Selected strains can adhere to mucosal surfaces, make lactic
acid and other antimicrobial substances, and help stabilise the gut barrier and immune
signalling. Clinical and preclinical studies report that specific L. gasseri strains
can favourably modulate gut microbiota, support markers of intestinal and metabolic health,
and help shift the vaginal microbiota toward a Lactobacillus-dominant, low-pH pattern in
women when taken orally as probiotics.1–3

Why we use it in Women's Probiotics

In Women’s Probiotics, L. gasseri is used as a key “axis” strain linking gut,
vaginal and metabolic support. Its role is to help maintain a Lactobacillus-rich vaginal
ecosystem and comfortable pH from the inside out, while also backing everyday gut-barrier
integrity and healthy inflammatory and metabolic tone. Together with other Lactobacillus
species in this blend, it contributes to daily microbial balance and resilience that are
important for women’s urogenital and whole-body well-being.

References

1. Selle K et al. Probiotic properties of L. gasseri. FEMS Microbiol Rev. 2013.

2. Pérez M et al. Oral L. gasseri CECT 30648 and vaginal microbiota in women.
Microbiol Spectr. 2025.

3. Qi F et al. Oral L. gasseri TM13 helps restore vaginal health after BV.
Front Immunol. 2023.

What it is & general benefits

Lactobacillus rhamnosus is a lactic acid–producing probiotic that naturally inhabits
the human gut and vaginal tract. Well-characterised strains such as L. rhamnosus GG
can adhere to intestinal cells, help stabilise the gut barrier, produce antimicrobial
substances and modulate immune signalling. Clinical studies show that selected
L. rhamnosus strains support digestive comfort, reduce the risk or duration of some
common infections and can help maintain healthy vaginal and urinary tract balance in
women.1–3

Why we use it in Women's Probiotics

In Women’s Probiotics, L. rhamnosus is positioned as a core “defence” strain along
the gut–vaginal–urinary axis. Its role is to help maintain a Lactobacillus-rich, low-pH
environment that makes it harder for disruptive bacteria and yeasts to dominate, while also
backing mucosal immune resilience. Combined with other Lactobacillus species in this blend,
it contributes to everyday comfort and recurrent-balance support for the vaginal and urinary
tracts, starting from the gut where many Lactobacilli first colonise.

References

1. Segers ME, Lebeer S. Probiotics in the gut: focus on L. rhamnosus GG.
Microb Cell Fact. 2014.

2. Falagas ME et al. Probiotics for the prevention of urinary tract infections in women.
Drugs. 2006.

3. Martinez RC et al. Oral L. rhamnosus GR-1 and vaginal microbiota balance.
Appl Environ Microbiol. 2009.

What it is & general benefits

Often labelled as Bifidobacterium lactis, this species (formally
B. animalis subsp. lactis) is one of the best-studied human
bifidobacteria. It naturally inhabits the gut and is widely used in probiotic
supplements and fermented dairy foods. Well-characterised strains such as HN019
and BB-12 can survive passage through the gastrointestinal tract, increase total
gut bifidobacteria, support bowel regularity and help reinforce the intestinal
barrier and immune responses in clinical studies on adults and children.1,2

Why we use it in Women's Probiotics

In Women’s Probiotics, B. lactis is used as a gut-focused “base strain”
that supports the rest of the formula. By promoting a bifidobacteria-rich colon,
healthy motility and a more resilient gut barrier, it helps stabilise the gut side
of the gut–vaginal–immune axis. This background support is important for women
whose digestion, immunity or metabolic markers are challenged by modern lifestyles,
and it complements the more vaginal-specialised Lactobacillus strains in the blend.

References

1. Cheng J et al. B. animalis subsp. lactis HN019 and gut health: a review.
Nutrients. 2021.

2. Collins FWJ et al. Probiotic mechanisms and clinical benefits of
B. animalis subsp. lactis BB-12. Front Microbiol. 2025.

3. Wang Q et al. Immune and metabolic effects of B. animalis subsp. lactis
in adults. Clin Nutr. 2025.

What it is & general benefits

Bifidobacterium bifidum is a typical human-derived bifidobacterial species that
colonises the large intestine early in life and is widely used as a probiotic. It ferments
dietary fibres into lactic acid and short-chain fatty acids, helping to nourish colon cells,
keep stool soft and maintain an acidic environment that favours beneficial microbes.
Clinical trials with specific B. bifidum strains have reported improvements in
constipation- or IBS-like gastrointestinal discomfort and favourable changes in gut
microbiota and inflammatory markers when taken regularly.1–3

Why we use it in Women's Probiotics

In Women’s Probiotics, B. bifidum is positioned as a gut–comfort and barrier
support strain. Its role is to back up regular bowel movements, support a bifidobacteria-rich
colon and help maintain a calm, well-sealed intestinal lining. A more stable gut environment
is an important foundation for the gut–vaginal–immune axis, so this strain works in the
background to support everyday digestive comfort, bloat control and immune balance that are
especially relevant to women under modern lifestyle stress.

References

1. Chen J et al. Probiotic Bifidobacterium species and human health.
Front Microbiol. 2021.

2. Wang L et al. B. bifidum CCFM16 relieves constipation in adults:
randomized controlled trial. Food Funct. 2022.

3. Gomi A et al. Fermented milk with B. bifidum YIT 10347 improves
gastrointestinal discomfort in healthy adults. J Dairy Sci. 2018.

What it is & general benefits

Bifidobacterium breve is a human-origin bifidobacterial species that naturally
colonises the infant and adult colon. It ferments fibres and human milk oligosaccharides into
lactic acid and short-chain fatty acids, which help nourish colon cells, keep stools soft and
maintain an acidic environment that favours beneficial microbes. Clinical and preclinical
studies with specific B. breve strains show support for bowel regularity, improved
gut-microbiota balance and modulation of immune and inflammatory markers, including in people
with constipation- or IBS-like discomfort and in children with atopic tendencies.1–3

Why we use it in Women's Probiotics

In Women’s Probiotics, B. breve is used as a gut–comfort and immune-support strain
that complements B. lactis and B. bifidum. Its role is to help fine-tune
colonic fermentation, ease bloating and irregularity, and support a calm immune tone at the
gut level. A more stable, bifidobacteria-rich colon is an important base for the
gut–vaginal–skin axis, so this strain works in the background to support everyday digestive
comfort, skin-friendly inflammation control and overall resilience in women.

References

1. O’Neill I et al. B. breve: key functions in the human gut.
Benef Microbes. 2020.

2. Kim SW et al. B. breve strain for IBS-like symptoms in adults:
randomized trial. World J Gastroenterol. 2021.

3. Namba K et al. B. breve M-16V and immune balance in children with atopy.
Asia Pac Allergy. 2018.

What it is & general benefits

Often classified as Bifidobacterium longum subsp. infantis, this
bifidobacterial species is a natural coloniser of the infant and adult gut. It specialises in
fermenting complex carbohydrates, including human milk oligosaccharides and dietary fibres,
into lactic acid and short-chain fatty acids that nourish colon cells and help maintain a
bifidobacteria-rich, acidic environment. Clinical studies with selected strains show support
for stool regularity, improved gut-microbiota composition and modulation of immune and
inflammatory markers in both infants and adults with functional gut discomfort or
immune-related issues.1–3

Why we use it in Women's Probiotics

In Women’s Probiotics, this strain is positioned as a gut–immune foundation strain with a
gentle, “nurturing” profile. Its role is to help build a bifidobacteria-dominant colon,
support regular, comfortable bowel movements and encourage a calmer immune tone starting in
the gut. A stable gut ecosystem is an important base for the gut–vaginal–skin axis, so this
strain works in the background to support everyday digestive comfort, bloat control and
overall resilience, especially relevant for women whose microbiota may have been shaped by
C-section birth, formula feeding, frequent antibiotics or modern lifestyle stress.

References

1. Underwood MA. Intestinal microbiota and human milk oligosaccharides: focus on
B. longum subsp. infantis. J Pediatr. 2019.

2. Berger B et al. Clinical benefits of B. longum subsp. infantis in infants
and adults: a review. Nutrients. 2020.

3. Nocerino R et al. Probiotic B. infantis and functional GI disorders in children.
Aliment Pharmacol Ther. 2019.

What it is & general benefits

This human-origin bifidobacterial species naturally colonises the large intestine and is one
of the dominant “core” genera in a healthy adult gut. It ferments dietary fibres into lactic
acid and short-chain fatty acids, which help nourish colon cells, keep stools soft and
maintain an acidic environment that favours beneficial microbes. Clinical studies with
selected strains show benefits for bowel regularity, improvements in gut-microbiota
composition and modulation of immune and inflammatory markers in adults with functional
digestive discomfort, stress-related symptoms or metabolic risk factors.1–3

Why we use it in Women's Probiotics

In Women’s Probiotics, this species is used as a key “stability” strain for the colon. Its
role is to help maintain a bifidobacteria-rich microbiota, support regular, comfortable bowel
movements and promote a calmer immune tone at the gut barrier. Because the gut strongly
influences the vaginal, urinary and skin microbiomes, this background stability is important
for women dealing with bloating, irregularity or modern lifestyle stress, and it complements
the more vaginal-focused Lactobacillus strains in the blend.

References

1. Arboleya S et al. Health effects of human-residential Bifidobacterium species.
Front Microbiol. 2016.

2. Xiao JZ et al. Clinical evidence for B. longum strains in functional bowel
symptoms and immune modulation. Nutrients. 2020.

3. Aoki R et al. Effects of probiotic B. longum on stress and gut function in adults.
J Funct Foods. 2022.

What it is & general benefits

This prebiotic fiber blend combines resistant starch from potato tuber with soluble acacia
fiber from Acacia senegal. Resistant starch escapes digestion in the small intestine
and is fermented in the colon into short-chain fatty acids (SCFAs) such as butyrate, which
nourish colon cells, support gut barrier integrity and promote the growth of beneficial
bacteria including Bifidobacterium and Lactobacillus.1,2 Acacia
fiber (gum arabic) is a gently fermentable soluble fiber that has been shown in human studies
to increase fecal bifidobacteria and lactobacilli and to be well tolerated at typical
prebiotic doses.3 Together, these fibers act as “food” for good microbes rather
than as laxative stimulants.

Why we use it in Women's Probiotics

In Women’s Probiotics, this blend is included to build a friendly environment for the
probiotic strains to thrive. By selectively feeding bifidobacteria and lactobacilli, it helps
the formula establish a more stable gut microbiota, supports regular and comfortable bowel
movements, and boosts SCFA production that can influence immune and metabolic balance from
the gut outward. This gut-level foundation is designed to work alongside the live cultures to
support the gut–vaginal axis, bloat control and day-to-day digestive comfort in women.

References

1. Kadyan S et al. Prebiotic mechanisms of resistant starches from dietary sources.
Front Nutr. 2023.

2. Hanes D et al. Gastrointestinal and microbiome impact of a resistant starch blend from
potato, banana and apple fibers: randomized clinical trial. Front Nutr. 2022.

3. Calame W et al. Gum arabic (Acacia senegal) establishes prebiotic functionality in healthy
human volunteers. Br J Nutr. 2008.