When to Use Fmlave NAD+ and When to Use Fmlave NMN 30000

John

Programer

I am going to answer plainly: I reach for Fmlave NAD+ when I want a daily, over-40, cardiovascular-and-inflammation-aware NAD strategy based on 500 mg nicotinamide riboside, because that is the dose range that actually moved vascular markers in middle-aged people [1]. I reach for Fmlave NMN 30000 when I want the 300 mg NMN human data, but I also want the “longevity vitamins” style co-factors — ergothioneine and spermidine — in the same capsule [5].

And yes — I actually ran the NAD+ bottle on myself for four weeks (German ancestry, so of course I kept a spreadsheet). Day-to-day I noted less post-work fatigue and a very undramatic but real improvement in “get-up speed” in the morning. That pattern is exactly what you would expect if you raise NAD+ while you also cool low-grade inflammation. I liked it enough to repeat the cycle.

What problem is each formula trying to solve?

Fmlave NAD+ — 60 capsules (2 caps/day)

500 mg NR to refill NAD⁺ in the same order of magnitude human NR trials used (500–1,000 mg/day) to improve arterial stiffness and systolic blood pressure in older adults [1].
Anti-inflammaging shell: quercetin phytosome 250 mg, resveratrol 150 mg, turmeric 50 mg, grape seed 100 mg, rose hips 100 mg, green tea 20 mg, acai 25 mg — this is textbook “reduce background NF-κB noise,” and quercetin phytosome actually has human data [3].
Absorption fix: black pepper 5 mg so the lighter polyphenol doses stay relevant.
Mito/adaptogen: shilajit 150 mg to make the NAD gain “feelable.”
Daily longevity flavor: fisetin 150 mg — not a pulsed senolytic, but an everyday nod.

Fmlave NMN 30000 — 30 capsules (1 cap/day)

NMN 300 mg — right in the band where we have 10–12 week human data for raising NAD⁺ and improving insulin sensitivity/muscle function [2].
Ergothioneine 25 mg — the compound we actively transport and concentrate in tissues with high oxidative stress, increasingly called a “longevity vitamin” [4].
Spermidine 1.2 mg — lower than the heroic research doses, but mechanistically pointing at autophagy; observational work on higher spermidine intakes in humans is promising [5].
SOD 10 mg (veg) — an extra antioxidant layer to support the NMN signal.
B12 + folate — tidy for daily use.

How do NR and NMN actually differ in humans?

Diagram showing NR-based and NMN-based NAD+ routes

What we know	NR (Fmlave NAD+)	NMN (Fmlave NMN 30000)
Product dose	500 mg NR/day (2 caps)	300 mg NMN/day (1 cap)
Human data anchor	NR 500–1,000 mg/day → ↑NAD⁺, ↓arterial stiffness/BP in middle-aged and older adults [1]	NMN 250–300 mg/day → ↑NAD⁺, ↑muscle insulin sensitivity/performance [2]
Extra supports	Quercetin phytosome, resveratrol, turmeric, grape seed, rose hips, green tea, acai, piperine, shilajit, D3	Ergothioneine, spermidine, SOD, B12, folate
Best for	40+ with creeping BP, stiffness, recovery fatigue, and obvious inflammaging	40–65 who want NAD + autophagy/oxidative-stress helpers in one capsule

So when should I pick Fmlave NAD+?

If the person in front of you looks like the subjects in the NR vascular studies — midlife or older, systolic pressure drifting up, “I’m not as fast to recover as I was at 35” — the NR-based bottle is the sane first choice [1]. I also like it when people have visible inflammation patterns because the quercetin-phytosome study is, frankly, a nice human anchor.

You want a 2-capsule morning routine that already includes polyphenols.
You want vascular + inflammatory + “I feel it” mitochondrial support in one SKU.
You are fine with a product that looks a bit “over-engineered” — as a German-heritage scientist I admit I like that.

When should I pick Fmlave NMN 30000?

If what you want is a clean, daily **NAD + geroprotective co-factor** hit in a single capsule, this is the one. It mirrors the 300 mg/day NMN work, then adds ergothioneine (for oxidation-prone tissues) [4] and spermidine (for the autophagy/pseudo-fasting story).

You prefer 1 capsule/day, no exceptions.
You are aiming at NAD + oxidative-stress + autophagy, not broad polyphenols.
You are selling to, or you are, a person who reads PubMed for fun.

Decision illustration NAD+ vs NMN

Can they be stacked?

Of course they can be stacked — but, speaking as someone who color-codes his supplementation log (it is very German, I know): daily NR + daily NMN is often more than a 40–60-year-old needs.

Daily base: Fmlave NAD+.
On training / fasting / travel days: add Fmlave NMN 30000.
Monitor redundancy: if another product already supplies similar polyphenols, remove them here.

Bottom line: NR bottle for vascular + inflammation + energy (with human anchors). NMN bottle for NAD + cell-maintenance co-factors. I tested the NR one on myself and the effect was modest but, importantly, repeatable — which is the only kind of effect I personally respect.