OYSTER PLUS

What is this ingredient? Vitamin B6 in supplements is often provided as pyridoxine, which the body converts into pyridoxal‑5′‑phosphate (PLP), its main active coenzyme form. PLP is required for more than 100 enzymatic reactions, especially in amino‑acid metabolism, neurotransmitter synthesis, and one‑carbon/transsulfuration pathways [1,2]. In the methionine–homocysteine cycle, PLP‑dependent enzymes help convert homocysteine to cystathionine and cysteine, linking B6 status to sulfur amino‑acid balance and downstream production of glutathione and other sulfur compounds [1,3,5].

Human depletion–repletion studies show that even moderate B6 restriction measurably alters circulating metabolites in one‑carbon and tryptophan catabolic pathways, with increases in cystathionine and changes in creatine/creatinine and dimethylglycine, indicating functional metabolic stress before overt deficiency symptoms appear [3,6]. Because PLP is also involved in glycogen breakdown, lipid metabolism, and erythropoiesis, maintaining adequate B6 is important for energy use and blood health as well as nervous‑system function [2,4].

Why include it in this formula? OYSTER PLUS is built around oyster extract, amino acids (taurine, methionine, glycine, arginine), Rhodiola, maca, saw palmetto, vitamin E, niacinamide, zinc (as glycine chelate), and B12, all suggesting a focus on male vitality, metabolic energy, and reproductive health. Within this architecture, vitamin B6 acts as a "protein and amino‑acid metabolism" pillar. PLP‑dependent enzymes help interconvert and utilize amino acids like methionine, glycine, and arginine, which are central to methylation, nitric oxide production, and structural protein synthesis [1,2,5].

By supporting transsulfuration and one‑carbon metabolism, B6 also complements B12 and niacinamide in maintaining homocysteine balance and fueling NAD‑ and methylation‑dependent pathways, which can affect vascular tone, energy, and hormone‑related signaling [1,2,3]. Paired with zinc from oyster extract and vitamin E, vitamin B6 helps ensure that the formula’s protein and mineral building blocks are backed by the enzymatic machinery needed to turn them into functional tissues and signaling molecules relevant to performance and male wellness.

References

• [1] Vitamin B6 deficiency, genome instability and cancer
• [2] Disorders affecting vitamin B6 metabolism
• [3] Metabolite profile analysis reveals functional effects of 28-day vitamin B-6 restriction on one-carbon metabolism and tryptophan catabolic pathways in healthy men and women
• [5] Vitamin B6 nutritional status and cellular availability of pyridoxal 5'-phosphate govern the function of the transsulfuration pathway's canonical reactions and hydrogen sulfide production via side reactions
• [6] Moderate vitamin B-6 restriction does not alter postprandial methionine cycle rates of remethylation, transmethylation, and total transsulfuration but increases the fractional synthesis rate of cystathionine in healthy young men and women

What is this ingredient? Vitamin B12 is a water‑soluble micronutrient that humans must obtain from food or supplements, especially animal-derived sources like shellfish and organ meats. Inside the body it is converted to the active coenzymes methylcobalamin and adenosylcobalamin, which are essential for one‑carbon metabolism and mitochondrial function. Vitamin B12 acts as a cofactor for methionine synthase in the folate–methionine cycle and for methylmalonyl‑CoA mutase in propionate metabolism, processes that underpin DNA synthesis, methylation, red blood cell production, and normal nervous‑system function [0,7].

Deficiency can disturb one‑carbon metabolism, elevate homocysteine, and compromise DNA stability and methylation patterns, and is associated with megaloblastic anemia and a wide range of neurological manifestations such as neuropathy, gait disturbance, cognitive changes, and mood symptoms [0,3,7]. Even before overt anemia appears, low B12 status can alter one‑carbon metabolites and may contribute to metabolic risk profiles in susceptible groups [5].

Why include it in this formula? OYSTER PLUS combines vitamin B6, vitamin B12, Rhodiola, taurine, vitamin E, niacinamide, zinc (as a glycine chelate, likely from oyster extract), methionine, glycine, arginine, saw palmetto, and maca—ingredients that point toward a focus on male vitality, metabolic energy, and reproductive health. Within this design, vitamin B12 is a core "one‑carbon and blood‑health" pillar. Together with B6 and the amino acid methionine, B12 supports homocysteine–methionine cycling, S‑adenosylmethionine (SAM) generation, and proper DNA synthesis in rapidly renewing tissues, including those of the reproductive and hematologic systems [0,1,7,9].

By contributing to normal red blood cell formation and oxygen‑carrying capacity, B12 also helps ensure that metabolically active tissues—such as skeletal muscle, the cardiovascular system, and reproductive organs—receive adequate oxygen while amino‑acid–rich components (oyster extract, arginine, taurine, methionine, glycine) provide structural and signaling substrates. In combination with niacinamide (NAD⁺ support), zinc, and adaptogens like Rhodiola and maca, vitamin B12 helps anchor this blend’s emphasis on energy, endurance, and hormone‑related wellness on a solid metabolic and genomic foundation.

References

• [0] Folate, vitamin B12 and vitamin B6 and one carbon metabolism
• [1] Nutritional vitamin B12 regulates RAS/MAPK‑mediated cell fate decisions through one‑carbon metabolism
• [3] Myths about vitamin B12 deficiency
• [5] Vitamin B12 deficiency and altered one‑carbon metabolites in early pregnancy is associated with maternal obesity and dyslipidaemia
• [7] Vitamin B12‑Multifaceted In Vivo Functions and In Vitro Applications
• [9] Methionine, homocysteine, one‑carbon metabolism and fetal growth

What is this ingredient? Rhodiola extract is derived from the root of Rhodiola rosea, a traditional adaptogenic herb used to support resilience under physical and mental stress. Its key constituents include rosavins and salidroside. Modern clinical research shows that standardized Rhodiola extracts can reduce fatigue, improve stress-related symptoms, and support mood. In a randomized, double‑blind, placebo‑controlled trial in people with stress‑related fatigue, 28 days of Rhodiola SHR‑5 extract significantly improved fatigue scores and several measures of attention compared with placebo []. Other controlled studies have reported reductions in stress, anxiety, and negative mood scores over 2–4 weeks, with good tolerability [].

Single‑dose and short‑term trials also indicate that Rhodiola can enhance physical performance under fatigue and may modestly improve strength and endurance metrics in resistance and aerobic tasks, though effects are generally small and most pronounced under stress conditions []. Overall, Rhodiola is best characterized as a gentle psychophysical adaptogen rather than a stimulant.

Why include it in this formula? OYSTER PLUS combines vitamin B6, vitamin B12, taurine, vitamin E, niacinamide, zinc (as a glycine chelate), oyster extract, methionine, glycine, arginine, saw palmetto, and maca—clearly targeting male vitality, energy, and reproductive health. Within this architecture, Rhodiola extract serves as the primary "stress‑resilience and fatigue" pillar. By reducing stress‑related fatigue, improving burnout scores, and supporting attentional performance in clinical trials [], Rhodiola helps users better access the benefits of structural and hormonal‑support nutrients in the blend.

Alongside oyster‑derived zinc, arginine and taurine (which support vascular and cellular function), and maca and saw palmetto (often used for male performance and prostate comfort), Rhodiola addresses the stress and exhaustion layer that can undermine libido, stamina, and mood. In combination with B‑vitamins and niacinamide that support mitochondrial and one‑carbon metabolism, Rhodiola extract rounds out the formula’s goal: promoting steady, stress‑resilient energy and male vitality rather than just short‑lived stimulation.

References

• [1] A randomised, double-blind, placebo-controlled, parallel-group study of the standardised extract SHR‑5 of the roots of Rhodiola rosea in the treatment of subjects with stress-related fatigue
• [2] A double-blind, placebo-controlled pilot study of the stimulating and adaptogenic effect of Rhodiola rosea SHR‑5 extract on the fatigue of students caused by stress during an examination period
• [3] The Effects of Rhodiola rosea L. Extract on Anxiety, Stress, Cognition and Other Mood Symptoms

What is this ingredient? Taurine is a sulfur‑containing amino acid–like compound that is abundant in excitable tissues such as the heart, skeletal muscle, retina, and brain. Unlike most amino acids, taurine is not incorporated into proteins; instead, it helps regulate cell volume, calcium flux, bile salt formation, and antioxidant defenses. It plays important roles in maintaining normal function of cardiac and skeletal muscle cells, stabilizing membranes, and supporting mitochondrial health and osmoregulation.

Dietary taurine comes primarily from animal foods like meat and seafood, and circulating levels can influence exercise capacity, fatigue resistance, and aspects of cardiometabolic health in at‑risk populations. Because it participates in bile salt conjugation, taurine also indirectly supports fat digestion and cholesterol handling.

Why include it in this formula? OYSTER PLUS combines vitamin B6 and B12, Rhodiola extract, vitamin E (d‑alpha‑tocopheryl succinate), niacinamide, zinc from oyster extract (via glycine chelate), and amino acids such as methionine, glycine, and arginine, plus saw palmetto and maca. Together, these ingredients point to a focus on male vitality, stamina, and cardiometabolic support. Within this architecture, taurine is a key "cellular fluid and heart–muscle" pillar. It helps buffer calcium handling and excitability in heart and skeletal muscle, which is relevant for physical performance and perceived energy.

Taurine’s role in bile salt conjugation and membrane stabilization also complements oyster‑derived minerals and the other amino acids in supporting vascular function and lipid metabolism. Paired with niacinamide (NAD⁺ support), vitamin E (lipid‑phase antioxidant), and adaptogens like Rhodiola and maca, taurine helps ensure that the formula doesn’t only address hormones and micronutrients, but also the underlying ionic and cellular environment that determines how strongly and efficiently muscles, including the heart, can perform day to day.

What is this ingredient? d‑alpha‑tocopheryl acid succinate is a stabilized, dry form of natural vitamin E (alpha‑tocopherol) in which the vitamin is esterified with succinic acid. In the body, it is converted to free alpha‑tocopherol, the principal fat‑soluble antioxidant vitamin in human cell membranes. Alpha‑tocopherol protects polyunsaturated fatty acids in phospholipids and lipoproteins from lipid peroxidation by scavenging lipid peroxyl radicals, thereby helping to maintain membrane integrity and normal cellular function [0,2].

Beyond its antioxidant role, vitamin E influences membrane properties and signal transduction, modulating enzyme activity and gene expression in a redox‑sensitive manner [0,1]. Experimental and observational research suggests that adequate circulating vitamin E is associated with lower markers of oxidative stress and, in some cohorts, a reduced risk of cardiovascular events, although high‑dose supplementation has produced mixed results in large outcome trials [0,2,8].

Why include it in this formula? OYSTER PLUS combines B6, B12, Rhodiola, taurine, niacinamide, zinc (as glycine chelate, largely from oyster extract), methionine, glycine, arginine, saw palmetto, and maca, pointing toward a focus on male vitality, metabolic energy, and reproductive health. Within this architecture, d‑alpha‑tocopheryl succinate is the main "lipid‑phase antioxidant" pillar. It helps protect cell and lipoprotein membranes in tissues central to male health—such as the testes, vasculature, and skeletal and cardiac muscle—from oxidative damage that can impair function [0,2].

By limiting lipid peroxidation, vitamin E complements niacinamide and B‑vitamins, which support mitochondrial and one‑carbon metabolism, and taurine, which stabilizes excitable membranes. It also pairs well with zinc and amino acids from oyster extract that are important for sperm membrane integrity and endocrine function. In this way, d‑alpha‑tocopheryl acid succinate helps create a more favorable oxidative environment around hormone‑sensitive and energy‑demanding tissues, supporting the product’s aim of steady, resilient male performance rather than brief stimulation.

References

• [0] Vitamin E: Regulatory Role on Signal Transduction
• [1] Antioxidant functions of vitamins. Vitamins E and C, beta‑carotene, and other carotenoids
• [2] α‑Tocopherol preserves cardiac function by reducing oxidative stress and inflammation in ischemia/reperfusion injury

What is this ingredient? Niacinamide (nicotinamide) is a non‑flushing form of vitamin B3. In the body it is converted into NAD⁺ and NADP⁺, central redox cofactors required for hundreds of dehydrogenase reactions and for the activity of enzymes such as PARPs and sirtuins that participate in DNA repair, gene regulation, and cellular stress responses []. Niacinamide therefore underpins core aspects of energy metabolism, redox balance, and cellular maintenance rather than acting as a stimulant.

Clinical work on nicotinamide has focused largely on specific contexts (for example, dermatologic and autoimmune indications or combinations with other NAD⁺ precursors). While trials of nicotinamide alone have not shown dramatic systemic performance effects in otherwise healthy adults, its biochemical role in maintaining NAD⁺ pools and supporting redox‑sensitive pathways is well established []. This makes niacinamide a foundational metabolic cofactor rather than a quick “energy shot.”

Why include it in this formula? OYSTER PLUS pairs B6, B12, Rhodiola, taurine, natural vitamin E, niacinamide, zinc (via glycine chelate, predominantly from oyster extract), methionine, glycine, arginine, saw palmetto, and maca. This combination clearly targets male vitality, metabolic energy, and reproductive health. Within this architecture, niacinamide is the main "NAD⁺ and redox" pillar. By feeding into the NAD⁺/NADP⁺ pool, it supports mitochondrial energy production and the activity of NAD‑dependent enzymes that help cells adapt to stress and repair everyday molecular damage [].

Niacinamide complements Rhodiola’s stress‑resilience effects, taurine’s membrane‑stabilizing and bile‑related roles, and zinc and amino acids from oyster extract that support endocrine, vascular, and reproductive tissues. When combined with B6 and B12, which help shape one‑carbon and amino‑acid metabolism, niacinamide helps ensure that this male‑focused blend has a solid biochemical backbone for energy, performance, and recovery, not just surface‑level symptom support.

References

• [1] Mechanistic Basis and Clinical Evidence for the Applications of Nicotinamide (Niacinamide) to Control Skin Aging and Pigmentation

What is this ingredient? “Glycine chelate” typically refers to a mineral—most often zinc in an oyster-focused formula—bound to the amino acid glycine. Chelating a mineral to glycine helps protect it as it travels through the digestive tract and can support more predictable absorption compared with some inorganic salts. In this product, the glycine chelate almost certainly represents a bioavailable form of zinc supplied alongside the naturally occurring trace minerals in oyster extract.

Glycine itself is a simple amino acid involved in collagen formation, glutathione synthesis, and inhibitory neurotransmission. When used as a chelating ligand, it primarily serves as a carrier for the mineral, while also contributing a small amount of additional glycine to the body’s amino‑acid pool.

Why include it in this formula? OYSTER PLUS combines B6, B12, Rhodiola, taurine, vitamin E, niacinamide, oyster extract, free-form methionine, glycine and arginine, plus saw palmetto and maca root—clearly targeting male vitality, performance, and reproductive health. Within this architecture, the glycine chelate is the "high‑bioavailability mineral" pillar, most importantly for zinc. Zinc is central to testosterone production, sperm quality, immune balance, and numerous enzyme systems relevant to male health; chelating it to glycine helps ensure efficient uptake from the gut, even in the presence of other nutrients.

Because the formula already includes free glycine, arginine, and methionine, providing zinc as a glycine chelate keeps the amino‑acid theme consistent while emphasizing absorption and tolerability. Paired with oyster extract (a natural source of zinc and trace minerals), B‑vitamins for energy metabolism, taurine for cellular stability, and adaptogens like Rhodiola and maca, the glycine chelate helps ensure that the critical trace‑mineral side of male vitality—especially zinc—is robustly and reliably covered.

What is this ingredient? Oyster extract is a concentrated powder made from edible oysters, typically providing naturally occurring zinc along with other trace minerals (such as copper, selenium, and manganese), amino acids, and small amounts of taurine and marine peptides. Oysters are among the richest natural dietary sources of zinc, an essential trace mineral involved in testosterone production, sperm development, immune function, and antioxidant enzyme systems.

Because it is derived from a whole food, oyster extract delivers zinc and its companion minerals in their native matrix, together with protein fragments that can contribute modestly to the body’s amino‑acid pool. This makes it a nutrient-dense marine ingredient, particularly aligned with male health and performance needs.

Why include it in this formula? Given the combination of vitamin B6 and B12, Rhodiola, taurine, natural vitamin E, niacinamide, a glycine‑chelated mineral, free-form methionine, glycine, arginine, saw palmetto, and maca, OYSTER PLUS is clearly focused on male vitality, stamina, and reproductive health. Within this architecture, oyster extract is the central "marine mineral and trace‑element" pillar, with zinc at its core. Adequate zinc status is critical for normal testosterone levels, sperm count and motility, and prostate health, and marginal deficiency is common in many adult diets.

By pairing whole‑food oyster extract with an additional highly bioavailable glycine chelate form of zinc, the formula strongly reinforces this trace‑mineral foundation while Rhodiola and maca address stress resilience and libido, and arginine and taurine support vascular and cellular function. B‑vitamins and niacinamide feed energy and methylation pathways, and vitamin E protects lipid membranes. In this way, oyster extract helps anchor the product in a traditional, food‑based source of male‑centric minerals while the rest of the blend builds out performance, hormonal, and energy support around it.

What is this ingredient? L‑Methionine is an essential sulfur‑containing amino acid that must come from the diet. It is the starting point for the methionine cycle, where it is converted to S‑adenosylmethionine (SAM), the body’s universal methyl donor for DNA, protein, and phospholipid methylation. Methionine is also a precursor for homocysteine, cysteine, taurine, creatine, carnitine, and glutathione, placing it at the center of one‑carbon and sulfur‑amino‑acid metabolism [0,3].

Through these pathways, methionine availability can influence antioxidant capacity, via glutathione and methionine sulfoxide reductases, and modulate inflammatory signaling and redox‑sensitive transcription factors such as Nrf2 in experimental models [1,3,5,6]. At the same time, excessive methionine intake without adequate B‑vitamins can promote homocysteine accumulation, so it is best used in the context of sufficient B6, B12, and folate to keep one‑carbon metabolism balanced [2,3].

Why include it in this formula? OYSTER PLUS brings together vitamin B6, vitamin B12, niacinamide, natural vitamin E, Rhodiola, taurine, zinc (via glycine chelate and oyster extract), free‑form glycine and arginine, saw palmetto, and maca root, clearly targeting male vitality, energy, and reproductive health. Within this architecture, L‑methionine is the core "methylation and sulfur‑backbone" amino acid. As the immediate precursor to SAM, it supports methylation reactions involved in hormone synthesis and metabolism, membrane phospholipid remodeling, and gene‑expression control—processes that underlie endocrine and reproductive function [0,2,3,5].

Because B6 and B12 are present, the formula also provides key cofactors to move methionine through the one‑carbon and transsulfuration pathways, helping to prevent unwanted homocysteine build‑up while feeding cysteine and glutathione synthesis for antioxidant defense [2,3,5]. Paired with taurine, glycine, arginine, zinc‑rich oyster extract, and adaptogens like Rhodiola and maca, L‑methionine helps provide both the sulfur and methyl "currency" needed for robust cellular energy, vascular and antioxidant support, and hormone‑related aspects of male performance.

References

• [0] The role of methionine on metabolism, oxidative stress, and diseases
• [1] L‑Methionine activates Nrf2‑ARE pathway to induce endogenous antioxidant activity for depressing ROS‑derived oxidative stress in growing rats
• [2] One carbon metabolism and bone homeostasis and remodeling: a review of experimental research and population studies
• [3] Methionine Attenuates Lipopolysaccharide‑Induced Inflammatory Responses via DNA Methylation in Macrophages
• [6] L‑Methionine Protects against Oxidative Stress and Mitochondrial Dysfunction in an In Vitro Model of Parkinson's Disease

What is this ingredient? L‑Glycine is the simplest amino acid and is considered “conditionally essential” because, although the body can synthesize it, demand can exceed endogenous production under states of rapid growth, repair, or metabolic stress. Glycine is a major component of collagen (about one-third of collagen’s amino acids) and is required for the synthesis of glutathione, creatine, heme, and purines. In the nervous system it acts as an inhibitory neurotransmitter and a co‑agonist at NMDA receptors, contributing to neuromodulation and sleep quality. In metabolic pathways, glycine helps buffer methylation demand by participating in one‑carbon metabolism and conjugation reactions (for example, forming bile acid conjugates and detoxification end‑products).

Because of its roles in collagen structure, antioxidant defense, and neuromodulation, supplemental L‑glycine is often used to support connective tissue integrity, sleep and recovery, and overall metabolic balance.

Why include it in this formula? OYSTER PLUS combines B6, B12, niacinamide, Rhodiola, taurine, vitamin E, zinc via oyster extract and glycine chelate, plus L‑methionine, L‑arginine, saw palmetto, and maca—clearly positioning the product around male vitality, stamina, and reproductive health. Within this architecture, L‑glycine is a versatile "structural and recovery" amino acid. It provides collagen‑rich building blocks for connective tissues, vessel walls, and joint and tendon support that matter for physical performance, while also feeding glutathione production and phase‑II conjugation pathways that help manage oxidative and metabolic stress.

Glycine pairs synergistically with methionine in one‑carbon and sulfur amino‑acid metabolism, with taurine and arginine in supporting vascular tone and cellular signaling, and with zinc and B‑vitamins in maintaining healthy testosterone‑related and hematologic function. By contributing to both the structural matrix (via collagen) and the recovery side (via glutathione and sleep‑related neuromodulation), L‑glycine helps ensure that the formula supports not just acute performance, but also nightly repair and long‑term resilience for male energy and vitality.

What is this ingredient? L‑Arginine is a conditionally essential amino acid best known as the primary substrate for nitric oxide (NO) synthase, the enzyme family that produces nitric oxide in blood vessels and other tissues. Nitric oxide is a key signaling molecule that promotes vasodilation, helping blood vessels relax and support healthy blood flow and blood pressure. Arginine is also required for creatine synthesis, the urea cycle (removal of ammonia), and the production of polyamines important for cell growth and tissue repair.

Because of its central role in NO production and vascular biology, L‑arginine has been widely studied in the context of endothelial function, exercise performance, and male sexual health. It does not act like a stimulant, but instead provides raw material for pathways that regulate circulation and nutrient delivery to active tissues.

Why include it in this formula? OYSTER PLUS combines vitamin B6 and B12, Rhodiola extract, taurine, natural vitamin E, niacinamide, zinc (via glycine chelate and oyster extract), L‑methionine, L‑glycine, saw palmetto, and maca root—clearly targeting male vitality, stamina, and reproductive health. Within this architecture, L‑arginine is the core “circulation and performance” amino acid. By feeding NO synthase, arginine supports vasodilation and blood flow to muscles and reproductive organs, which is directly relevant for physical performance and sexual function.

Arginine works synergistically with taurine (membrane and calcium handling), zinc from oyster extract (testosterone and sperm health), and adaptogens like Rhodiola and maca (stress resilience and libido). B‑vitamins and niacinamide support the mitochondrial and redox pathways that use the improved circulation to generate usable energy. In this way, L‑arginine helps translate the product’s hormonal, mineral, and adaptogenic support into practical benefits for stamina, vascular health, and male vitality.

What is this ingredient? Saw palmetto berry extract is derived from the fruit of Serenoa repens, a small palm native to the southeastern United States. The lipid extract contains free fatty acids and phytosterols that can inhibit 5‑α‑reductase and modulate androgen signaling in prostate tissue in experimental models. Because of these properties, saw palmetto has been widely used for lower urinary tract symptoms (LUTS) associated with benign prostatic hyperplasia (BPH).

Clinical data are mixed: some randomized trials and earlier meta‑analyses suggested modest symptom improvements compared with placebo, while larger, more rigorous studies—such as the CAMUS trial and other high‑dose trials up to triple the standard dose—found no significant advantage over placebo for LUTS outcomes, although safety was good [0,3,4,9]. Newer formulations enriched with β‑sitosterol have shown symptom and androgen‑related improvements in men with BPH over 12 weeks in controlled studies, indicating that specific standardized extracts may have more pronounced effects [7]. Overall, saw palmetto is best viewed as a well‑tolerated phytosterol‑rich extract with potential, but not guaranteed, support for prostate‑related symptoms.

Why include it in this formula? OYSTER PLUS combines B6, B12, Rhodiola, taurine, vitamin E, niacinamide, zinc (glycine chelate and oyster extract), methionine, glycine, arginine, saw palmetto, and maca root—clearly targeting male vitality, circulation, and reproductive health. Within this architecture, saw palmetto berry extract is the primary "prostate and androgen‑balance" pillar. By partially inhibiting 5‑α‑reductase and influencing local androgen activity in prostate tissue, it is intended to support urinary comfort and prostate health in the context of aging male physiology [1,7,9].

It works alongside zinc and oyster extract, which support testosterone metabolism and sperm parameters; arginine and taurine, which aid vascular function; and Rhodiola and maca, which are chosen for stress resilience and libido. Even though clinical outcomes with saw palmetto vary, its long history of use, favorable safety profile, and mechanistic plausibility make it a logical inclusion as the phytotherapeutic component aimed specifically at the prostate within this broader male‑health complex.

References

• [0] Saw palmetto extracts for treatment of benign prostatic hyperplasia: a systematic review
• [3] Effect of increasing doses of saw palmetto extract on lower urinary tract symptoms: a randomized trial
• [4] Safety and toxicity of saw palmetto in the CAMUS trial
• [7] A double blind, placebo-controlled randomized comparative study on the efficacy of phytosterol-enriched and conventional saw palmetto oil in mitigating benign prostate hyperplasia and androgen deficiency
• [9] Serenoa repens extract for benign prostate hyperplasia: a randomized controlled trial

What is this ingredient? Maca root comes from Lepidium meyenii, a cruciferous plant native to the high Andes of Peru. Traditionally consumed as a food, dried maca root is rich in carbohydrates, some protein, minerals, and unique macamides and macaenes—lipidic compounds thought to underlie many of its functional effects. Modern human studies suggest maca can support aspects of sexual well‑being, mood, and perceived energy, particularly in men.

Clinical trials in otherwise healthy men have reported improvements in self‑rated sexual desire and well‑being over several weeks of daily maca supplementation, often without large changes in serum testosterone. Other small studies suggest benefits for sperm concentration and motility, and for mood and quality‑of‑life scores in people under stress or with antidepressant‑associated sexual dysfunction. Overall, maca is best described as a food‑grade adaptogenic root with particular relevance for sexual vitality.

Why include it in this formula? OYSTER PLUS combines vitamins B6 and B12, Rhodiola extract, taurine, natural vitamin E, niacinamide, zinc (via glycine chelate and oyster extract), L‑methionine, L‑glycine, L‑arginine, saw palmetto, and maca root. This constellation clearly targets male vitality, stamina, circulation, and reproductive health. Within that architecture, maca root is the "libido and reproductive vitality" pillar. While oyster extract and zinc focus on testicular and sperm parameters, and arginine supports blood flow, maca contributes a traditionally grounded, human‑studied boost to sexual desire, subjective energy, and overall male well‑being.

By acting more on central and psychological aspects of sexuality and resilience, maca complements Rhodiola’s stress‑adaptation role and the metabolic support from B‑vitamins and niacinamide. In combination with saw palmetto for prostate comfort and taurine for cellular stability, maca helps ensure that the formula addresses not only the mechanical and hormonal sides of male health, but also how energized, motivated, and sexually engaged the user feels day to day.